IMMUNOCOMPROMISED FLU STUDY

What Is This About?

High-Risk or Immunocompromised? You may qualify for an Influenza research study (ages 12+).
If you (or someone you love) keeps getting turned down for studies, this one may be different. We’re screening participants with certain higher-risk non-immunocompromised conditions and immunocompromised conditions—if you’re medically stable, not needing significant changes in therapy, and haven’t been hospitalized for worsening disease or a major event in the last 2 months.

WE ARE CURRENTLY SCREENING IN PREPARATION FOR THE STUDY KICK-OFF. AS WE RECEIVE MORE DETAILED INFORMATION, WE WILL POST IT ON OUR WEBSITE.

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Who Can Join?

Eligibility Criteria

There are several flu studies we'll be offering including some for healthy patients aged 18+ as well as aged 12+ up for higher-risk non-immunocompromised or immunocompromised conditions.

Group A: Higher-risk, non-immunocompromised
(Must NOT have received the current flu vaccine within the last 6 months)
• Chronic pulmonary disease (COPD, chronic bronchitis, cystic fibrosis, IPF)
• Persistent asthma requiring daily therapy
• Cardiac disease (CHF, congenital heart disease, coronary artery disease)
• Neurologic disorder (not incl. Alzheimer’s/dementia) or history of stroke
• Diabetes
• Chronic renal impairment (eGFR < 60 mL/min; not on hemodialysis)
• Chronic liver disorder (not worse than Child-Pugh Class A)
• BMI ≥ 40 kg/m²

Group B: Immunocompromised
(Must HAVE received the current flu vaccine ≥14 days before study drug)
• Solid tumor cancer on immunosuppressive treatment
• Hematologic malignancy
• Transplant (solid organ or hematopoietic cell) within 2 years, and/or chronic GVHD
• Transplant >2 years ago may be eligible based on current immunosuppressive treatment
• Receiving immunosuppressive meds (e.g., ≥20 mg prednisone/day or equivalents; alkylating agents; antimetabolites; transplant-related agents; certain chemo incl. BTK inhibitors; TNF blockers; other immunosuppressive biologics)
• Prior CAR-T therapy
• B-cell depleting therapies in past 12 months (e.g., rituximab, ocrelizumab, ofatumumab, alemtuzumab)
• Moderate/severe primary or secondary immunodeficiency (e.g., hemodialysis)
• Advanced or untreated HIV with CD4 counts >200/mm³ (within 6 months of screening)

Other Details:

Health: Must be in generally good health with no serious allergies to vaccines.
Willingness: Must agree to follow the study plan and attend all check-ins. (5 in-office visits, 3 remote phone calls)
Other factors: Can’t be sick at the time of the shot or have other major health issues that would interfere with the study. (During screening we can determine what is acceptable)

Joining a study like this gives researchers the information they need to build better flu shots for future seasons, protect more lives, and help people stay healthier during flu outbreaks. It’s a way to make a real difference in public health.

Important Things to Know

💵 Compensation provided for your time and travel
💉 No insurance required to participate
🩺 All study-related care and exams are provided at no cost
📅 Participation includes multiple visits over a few weeks or months
✍️ You’ll need to give informed consent before enrolling

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Sign Up For Studies in Plano, TX

Support Science & Get Rewarded – Join Our Ambassador Program 💵

Do you know someone who may qualify for a clinical research study?

Our Ambassador Program is a simple way for you to help advance medical research—and get rewarded for it.

When you refer someone new to Research Your Health and they qualify and participate in a study, you’ll earn $100 per referral as a thank-you for your support. There’s no limit to how many people you can refer.

By spreading the word, you’re not only helping friends and family access no-cost medical care, lab testing, and cutting-edge treatments, but you're also contributing to scientific breakthroughs that can benefit future generations.

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What to Expect in a Clinical Trial

Step-by-step Walkthrough

We understand that participating in a clinical trial might feel overwhelming, especially if it's your first time. At RYH, we are committed to making the process as seamless and transparent as possible. Our goal is to ensure that you feel comfortable, informed, and supported throughout your journey with us.

Clinical trials play a vital role in the advancement of medicine, helping to develop innovative treatments and improve healthcare for future generations. By volunteering, you contribute to groundbreaking research that has the potential to change lives.

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All hands in to enroll in research studies

Benefits of Clinical Trial Participation

Joining a Trial offers several advantages, including:

Contributing to Medical Advancements – Help drive progress in the development of new treatments and therapies.
Early Access to Cutting-Edge Treatments – Receive potential new medications and procedures before they become publicly available.
Comprehensive Health Evaluations – Benefit from in-depth medical assessments as part of the study process.
Support for Better Health – Gain insights into managing your well-being and overall health.
Financial Compensation – Many studies provide monetary compensation for your time and participation.

Study Steps

Participating in a clinical trial is simple and safe. First, we’ll guide you through a screening process to see if you qualify, which may include a short questionnaire or basic health tests. If eligible, you’ll be scheduled for study visits where you’ll receive the study treatment or intervention at no cost. There’s no insurance required and no payment on your part to participate. Our medical team will monitor your progress closely to ensure your safety, and you’re free to withdraw from the study at any time.

Doctor enrolling patient into research study

Screening Visits

Once you meet the initial qualifications for one of our paid clinical trials, you’ll be invited to come in for a screening visit. During this visit, you’ll receive detailed information about the study, and our team will answer any questions you have. Participation is completely voluntary. If you choose to move forward, you’ll be asked to sign a consent form. Depending on the study, we may perform health assessments such as a urine sample, ECG, or lab tests to confirm your eligibility.

Office Visits

If you qualify for the study, you’ll return for scheduled office visits where the study medication may be given, and tests will be performed to evaluate how it’s working. These visits typically include brief check-ups, medical monitoring, and may involve an exam, lab work, or a blood pressure check—depending on the study. Visits can take place over several days or stretch out over a few months. You’ll receive compensation for your time and travel at the end of each visit.

Diaries & Phone Calls

To help track your progress during the study, you may be asked to use an app or complete a digital diary to record important information like how you’re feeling or if you’ve experienced any side effects. This helps our team monitor your health between visits. In some cases, we’ll also schedule brief phone calls to check in—no need to come into the office for these.

Compensation

At RYH, we truly value our volunteers who play a vital role in helping advance potentially life-saving therapies. In addition to receiving complimentary study-related care throughout your participation, you may also be compensated for your time and travel.

If you're interested in participating in paid clinical trials in the Plano/Dallas area or want to find out which studies you may qualify for, contact us at [email protected] or call/text 972-638-7879. Our friendly team is here to answer your questions and help you make a meaningful impact in advancing health through research.